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Differential contributions of peripheral and central mechanisms to pain in a rodent model of osteoarthritis

The mechanisms underlying the transition from acute nociceptive pain to centrally maintained chronic pain are not clear. We have studied the contributions of the peripheral and central nervous systems during the development of osteoarthritis (OA) pain. Male Sprague-Dawley rats received unilateral in...

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Publicado en:Sci Rep
Autores principales: Haywood, Adrian R., Hathway, Gareth J., Chapman, Victoria
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940779/
https://ncbi.nlm.nih.gov/pubmed/29740093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25581-8
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