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Neuron-immune mechanisms contribute to pain in early stages of arthritis

BACKGROUND: Rheumatoid arthritis (RA) patients frequently show weak correlations between the magnitude of pain and inflammation suggesting that mechanisms other than overt peripheral inflammation contribute to pain in RA. We assessed changes in microglial reactivity and spinal excitability and their...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Nieto, Francisco R., Clark, Anna K., Grist, John, Hathway, Gareth J., Chapman, Victoria, Malcangio, Marzia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851814/
https://ncbi.nlm.nih.gov/pubmed/27130316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0556-0
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