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Phasic dopamine signals in the nucleus accumbens that cause active avoidance require endocannabinoid mobilization in the midbrain

Phasic dopamine (DA) release accompanies approach towards appetitive cues. However, a role for DA in the active avoidance of negative events remains undetermined. Warning signals informing footshock avoidance are associated with accumbal DA release, while depression of DA is observed with unavoidabl...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Wenzel, Jennifer M, Oleson, Erik B, Gove, Willard N, Cole, Anthony B, Gyawali, Utsav, Dantrassy, Hannah M., Bluett, Rebecca J, Dryanovski, Dilyan I, Stuber, Garret D, Deisseroth, Karl, Mathur, Brian N, Patel, Sachin, Lupica, Carl R, Cheer, Joseph F
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940536/
https://ncbi.nlm.nih.gov/pubmed/29681476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2018.03.037
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