A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells

Adaptive immunity is initiated by T cell recognition of specific antigens presented by major histocompatibility complexes (MHCs). MHC multimer technology has been developed for the detection, isolation, and characterization of T cells in infection, autoimmunity, and cancer. Here, we present a simple...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Luimstra, Jolien J., Garstka, Malgorzata A., Roex, Marthe C.J., Redeker, Anke, Janssen, George M.C., van Veelen, Peter A., Arens, Ramon, Falkenburg, J.H. Frederik, Neefjes, Jacques, Ovaa, Huib
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940271/
https://ncbi.nlm.nih.gov/pubmed/29666167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180156
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