Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation

GATA-binding protein 3 (GATA3) acts as the master transcription factor for type 2 T helper (Th2) cell differentiation and function. However, it is still elusive how GATA3 function is precisely regulated in Th2 cells. Here, we show that the transcription factor B cell lymphoma 11b (Bcl11b), a previou...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Fang, Difeng, Cui, Kairong, Hu, Gangqing, Gurram, Rama Krishna, Zhong, Chao, Oler, Andrew J., Yagi, Ryoji, Zhao, Ming, Sharma, Suveena, Liu, Pentao, Sun, Bing, Zhao, Keji, Zhu, Jinfang
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940260/
https://ncbi.nlm.nih.gov/pubmed/29514917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171127
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