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The transcription factor Bhlhe40 is a switch of inflammatory versus antiinflammatory Th1 cell fate determination
Type 1 T helper (Th1) cells play a critical role in host defense against intracellular pathogens and in autoimmune diseases by producing a key inflammatory cytokine interferon (IFN)–γ; some Th1 cells can also be antiinflammatory through producing IL-10. However, the molecular switch for regulating t...
Enregistré dans:
| Publié dans: | J Exp Med |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Rockefeller University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028509/ https://ncbi.nlm.nih.gov/pubmed/29773643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170155 |
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