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Effect of combining glucocorticoids with Compound A on glucocorticoid receptor responsiveness in lymphoid malignancies

Glucocorticoids (GCs) are a cornerstone in the treatment of lymphoid malignancies such as multiple myeloma (MM) and acute lymphoblastic leukemia (ALL). Yet, prolonged GC use is hampered by deleterious GC-related side effects and the emergence of GC resistance. To tackle and overcome these GC-related...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Clarisse, Dorien, Van Wesemael, Karlien, Tavernier, Jan, Offner, Fritz, Beck, Ilse M., De Bosscher, Karolien
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940183/
https://ncbi.nlm.nih.gov/pubmed/29738549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197000
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