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The evolution of CpG density and lifespan in conserved primate and mammalian promoters
Gene promoters are evolutionarily conserved across holozoans and enriched in CpG sites, the target for DNA methylation. As animals age, the epigenetic pattern of DNA methylation degrades, with highly methylated CpG sites gradually becoming demethylated while CpG islands increase in methylation. Acro...
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| Publicado no: | Aging (Albany NY) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940106/ https://ncbi.nlm.nih.gov/pubmed/29661983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101413 |
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