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ancGWAS: a post genome-wide association study method for interaction, pathway and ancestry analysis in homogeneous and admixed populations

Motivation: Despite numerous successful Genome-wide Association Studies (GWAS), detecting variants that have low disease risk still poses a challenge. GWAS may miss disease genes with weak genetic effects or strong epistatic effects due to the single-marker testing approach commonly used. GWAS may t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bioinformatics
Main Authors: Chimusa, Emile R., Mbiyavanga, Mamana, Mazandu, Gaston K., Mulder, Nicola J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939890/
https://ncbi.nlm.nih.gov/pubmed/26508762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv619
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