Human Abuse Potential of an Abuse-Deterrent (AD), Extended-Release (ER) Morphine Product Candidate (Morphine-ADER Injection-Molded Tablets) vs Extended-Release Morphine Administered Intranasally in Nondependent Recreational Opioid Users

Objective. To compare the relative human abuse potential after insufflation of manipulated morphine abuse-deterrent, extended-release injection-molded tablets (morphine-ADER-IMT) with that of marketed morphine ER tablets. Methods. A randomized, double-blind, double-dummy, active- and placebo-control...

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Bibliographic Details
Published in:Pain Med
Main Authors: Webster, Lynn R., Smith, Michael D., Lawler, John, Lindhardt, Karsten, Dayno, Jeffrey M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
OPIOIDS & SUBSTANCE USE DISORDERS SECTION
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939830/
https://ncbi.nlm.nih.gov/pubmed/27651510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/pm/pnw219
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