Human Abuse Potential of an Abuse-Deterrent (AD), Extended-Release (ER) Morphine Product Candidate (Morphine-ADER Injection-Molded Tablets) versus Extended-Release Morphine Administered Orally in Nondependent Recreational Opioid Users

Objective. To compare the relative human abuse potential of intact and manipulated morphine abuse-deterrent, extended-release injection-molded tablets (morphine-ADER-IMT) with that of marketed morphine sulfate ER tablets Methods. This randomized, double-blind, triple-dummy, active- and placebo-contr...

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Vydáno v:Pain Med
Hlavní autoři: Smith, Michael D., Webster, Lynn R., Lawler, John, Lindhardt, Karsten, Dayno, Jeffrey M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
OPIOIDS, SUBSTANCE ABUSE & ADDICTIONS SECTION
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431384/
https://ncbi.nlm.nih.gov/pubmed/27633773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/pm/pnw174
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