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Extended Half-Life Factor VIII and Factor IX Preparations

In the last couple of years, several extended half-life factor VIII and factor IX preparations were intensively studied and gained approval. In order to extend half-lives, techniques like fusion to protein conjugates (Fc part of IgG(1) or albumin), chemical modification (PEGylation), and protein seq...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Transfus Med Hemother
Prif Awdur: Graf, Lukas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: S. Karger GmbH 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939656/
https://ncbi.nlm.nih.gov/pubmed/29765290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000488060
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