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Extended Half-Life Factor VIII and Factor IX Preparations
In the last couple of years, several extended half-life factor VIII and factor IX preparations were intensively studied and gained approval. In order to extend half-lives, techniques like fusion to protein conjugates (Fc part of IgG(1) or albumin), chemical modification (PEGylation), and protein seq...
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| Udgivet i: | Transfus Med Hemother |
|---|---|
| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
S. Karger GmbH
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5939656/ https://ncbi.nlm.nih.gov/pubmed/29765290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000488060 |
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