Antigenic Characterization of a Novel Recombinant GII.P16-GII.4 Sydney Norovirus Strain With Minor Sequence Variation Leading to Antibody Escape

BACKGROUND: Human noroviruses are the leading cause of acute gastroenteritis. Strains of the GII.4 genotype cause pandemic waves associated with viral evolution and subsequent antigenic drift and ligand-binding modulation. In November 2015, a novel GII.4 Sydney recombinant variant (GII.P16-GII.4 Syd...

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Publicat a:J Infect Dis
Autors principals: Lindesmith, Lisa C, Brewer-Jensen, Paul D, Mallory, Michael L, Debbink, Kari, Swann, Excel W, Vinjé, Jan, Baric, Ralph S
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939617/
https://ncbi.nlm.nih.gov/pubmed/29281104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix651
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