Ablation of beta subunit of protein kinase CK2 in mouse oocytes causes follicle atresia and premature ovarian failure

Premature ovarian failure (POF), a major cause of female infertility, is a complex disorder, but the molecular mechanisms underlying the disorder are only poorly understood. Here we report that protein kinase CK2 contributes to maintaining follicular survival through PI3K/AKT pathway and DNA damage...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Liang, Qiu-Xia, Wang, Zhen-Bo, Lin, Fei, Zhang, Chun-Hui, Sun, Hong-Mei, Zhou, Liang, Zhou, Qian, Schatten, Heide, Odile, Filhol-Cochet, Brigitte, Boldyreff, Sun, Qing-Yuan, Qian, Wei-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938699/
https://ncbi.nlm.nih.gov/pubmed/29725001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0505-1
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