BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer

The bromodomain-containing protein 7 (BRD7) was first identified as a tumor suppressor in nasopharyngeal carcinoma and has critical roles in cancer development and progression. However, the regulatory roles and mechanisms of BRD7 in cancer metabolism are still unknown. In this study, we demonstrated...

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Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Niu, Weihong, Luo, Yanwei, Wang, Xinye, Zhou, Yao, Li, Hui, Wang, Heran, Fu, Yaojie, Liu, Shanshan, Yin, Shanghelin, Li, Jianglei, Zhao, Ran, Liu, Yukun, Fan, Songqing, Li, Zheng, Xiong, Wei, Li, Xiaoling, Li, Guiyuan, Ren, Caiping, Tan, Ming, Zhou, Ming
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938698/
https://ncbi.nlm.nih.gov/pubmed/29725006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0536-7
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