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BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer

The bromodomain-containing protein 7 (BRD7) was first identified as a tumor suppressor in nasopharyngeal carcinoma and has critical roles in cancer development and progression. However, the regulatory roles and mechanisms of BRD7 in cancer metabolism are still unknown. In this study, we demonstrated...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Niu, Weihong, Luo, Yanwei, Wang, Xinye, Zhou, Yao, Li, Hui, Wang, Heran, Fu, Yaojie, Liu, Shanshan, Yin, Shanghelin, Li, Jianglei, Zhao, Ran, Liu, Yukun, Fan, Songqing, Li, Zheng, Xiong, Wei, Li, Xiaoling, Li, Guiyuan, Ren, Caiping, Tan, Ming, Zhou, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938698/
https://ncbi.nlm.nih.gov/pubmed/29725006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0536-7
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