Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

The evolutionary features of clear-cell renal cell carcinoma (ccRCC) have not been systematically studied to date. We analyzed 1,206 primary tumor regions from 101 patients recruited into the multi-center prospective study, TRACERx Renal. We observe up to 30 driver events per tumor and show that sub...

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Bibliografski detalji
Izdano u:Cell
Glavni autori: Turajlic, Samra, Xu, Hang, Litchfield, Kevin, Rowan, Andrew, Horswell, Stuart, Chambers, Tim, O’Brien, Tim, Lopez, Jose I., Watkins, Thomas B.K., Nicol, David, Stares, Mark, Challacombe, Ben, Hazell, Steve, Chandra, Ashish, Mitchell, Thomas J., Au, Lewis, Eichler-Jonsson, Claudia, Jabbar, Faiz, Soultati, Aspasia, Chowdhury, Simon, Rudman, Sarah, Lynch, Joanna, Fernando, Archana, Stamp, Gordon, Nye, Emma, Stewart, Aengus, Xing, Wei, Smith, Jonathan C., Escudero, Mickael, Huffman, Adam, Matthews, Nik, Elgar, Greg, Phillimore, Ben, Costa, Marta, Begum, Sharmin, Ward, Sophia, Salm, Max, Boeing, Stefan, Fisher, Rosalie, Spain, Lavinia, Navas, Carolina, Grönroos, Eva, Hobor, Sebastijan, Sharma, Sarkhara, Aurangzeb, Ismaeel, Lall, Sharanpreet, Polson, Alexander, Varia, Mary, Horsfield, Catherine, Fotiadis, Nicos, Pickering, Lisa, Schwarz, Roland F., Silva, Bruno, Herrero, Javier, Luscombe, Nick M., Jamal-Hanjani, Mariam, Rosenthal, Rachel, Birkbak, Nicolai J., Wilson, Gareth A., Pipek, Orsolya, Ribli, Dezso, Krzystanek, Marcin, Csabai, Istvan, Szallasi, Zoltan, Gore, Martin, McGranahan, Nicholas, Van Loo, Peter, Campbell, Peter, Larkin, James, Swanton, Charles
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938372/
https://ncbi.nlm.nih.gov/pubmed/29656894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.03.043
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