Evodiamine, a Novel NOTCH3 Methylation Stimulator, Significantly Suppresses Lung Carcinogenesis in Vitro and in Vivo

Lung cancer is a leading cause of cancer-related deaths worldwide. NOTCH3 signaling is mainly expressed in non-small cell lung carcinoma (NSCLC), and has been proposed as a therapeutic target of NSCLC. While, few agents for preventing or treating NSCLC via targeting NOTCH3 signaling are used in mode...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Su, Tao, Yang, Xia, Deng, Jian-Hua, Huang, Qiu-Ju, Huang, Su-Chao, Zhang, Yan-Min, Zheng, Hong-Ming, Wang, Ying, Lu, Lin-Lin, Liu, Zhong-Qiu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938359/
https://ncbi.nlm.nih.gov/pubmed/29765324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00434
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