Quantitative Characterization of Shear-Induced Platelet Receptor Shedding: Glycoprotein Ibα, Glycoprotein VI and Glycoprotein IIb/IIIa

The structural integrity of platelet receptors is essential for platelets to play the normal hemostatic function. The high non-physiological shear stress (NPSS) commonly exists in blood contacting medical devices and has been shown to cause platelet receptor shedding. The loss of platelet receptors...

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Veröffentlicht in:ASAIO J
Hauptverfasser: Chen, Zengsheng, Koenig, Steven C., Slaughter, Mark S., Griffith, Bartley P., Wu, Zhongjun J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938160/
https://ncbi.nlm.nih.gov/pubmed/29117043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAT.0000000000000722
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