High Shear Induces Platelet Dysfunction Leading to Enhanced Thrombotic Propensity and DiminishedHemostatic Capacity

Thrombosis and bleeding are devastating adverse events in patients supported with blood contacting medical devices (BCMDs). In this study, we delineated that high non-physiological shear stress (NPSS) caused platelet dysfunction that may contribute to both thrombosis and bleeding. Human blood was su...

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Detalhes bibliográficos
Publicado no:Platelets
Main Authors: Zengsheng, Chen, Mondal, Nandan K., Zheng, Shirong, Koenig, Steven C., Slaughter, Mark S., Griffith, Bartley P., Wu, Zhongjun J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108946/
https://ncbi.nlm.nih.gov/pubmed/29182470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09537104.2017.1384542
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