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DNA damage-associated oligodendrocyte degeneration precedes amyloid pathology and contributes to Alzheimer’s and dementia

INTRODUCTION: In looking for novel non-amyloid-based etiologies for Alzheimer’s disease we explore the hypothesis that age-related myelin loss is an attractive explanation for age-associated cognitive decline and dementia. METHODS: We performed a meta-analysis of data in the NACC database accompanie...

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Bibliografske podrobnosti
izdano v:Alzheimers Dement
Main Authors: Tse, Kai-Hei, Cheng, Aifang, Ma, Fulin, Herrup, Karl
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938117/
https://ncbi.nlm.nih.gov/pubmed/29328926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2017.11.010
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