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Optimization of (18)F-Syntheses using (19)F-Reagents at Tracer-level Concentrations and LC-MS/MS Analysis: Improved Synthesis of [(18)F]MDL100907
Traditional radiosynthetic optimization faces the challenges of high radiation exposure, cost and inability to perform serial reactions due to tracer decay. To accelerate tracer development, we have developed a strategy to simulate radioactive (18)F-syntheses by using tracer-level (nanomolar) non-ra...
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| Foilsithe in: | J Labelled Comp Radiopharm |
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| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2018
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5938101/ https://ncbi.nlm.nih.gov/pubmed/29336065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3606 |
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