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Dynamic phosphorylation of apoptosis signal regulating kinase 1 (ASK1) in response to oxidative and electrophilic stress

Apoptosis signal-regulating kinase 1 (ASK1) is a critical cellular stress sensor that senses diverse reactive chemotypes and integrates these chemical signals into a single biological pathway response. It is unknown whether ASK1 senses all stressors in the same way, or if unique stress-specific mech...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Betanzos, Carlos Morales, Federspiel, Joel D., Palubinsky, Amy M., McLaughlin, BethAnn, Liebler, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937698/
https://ncbi.nlm.nih.gov/pubmed/27989136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00339
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