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Artificial macrocycles as IL-17A/IL-17RA antagonists
Interleukin 17(A) is a pro-inflammatory cytokine involved in several auto-immune and inflammatory diseases. Current antagonists against IL-17(A) or its receptor (IL-17RA) that show efficacy in clinical trials are monoclonal antibodies (mAbs). However, recently designed artificial macrocycles are pot...
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| Publicado en: | Medchemcomm |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Royal Society of Chemistry
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5937545/ https://ncbi.nlm.nih.gov/pubmed/29750108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00464h |
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