Enhancing Sensitivity of Liquid Chromatography–Mass Spectrometry of Peptides and Proteins Using Supercharging Agents

Trifluoroacetic acid (TFA) is often used as a mobile phase modifier to enhance reversed phase chromatographic performance. TFA adjusts solution pH and is an ion-pairing agent, but it is not typically suitable for electrospray ionization-mass spectrometry (ESI-MS) and liquid chromatography/MS (LC/MS)...

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Detaylı Bibliyografya
Yayımlandı:Int J Mass Spectrom
Asıl Yazarlar: Nshanian, Michael, Lakshmanan, Rajeswari, Chen, Hao, Ogorzalek Loo, Rachel R., Loo, Joseph A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937529/
https://ncbi.nlm.nih.gov/pubmed/29750076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2017.12.006
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