Intranasal Pharmacokinetics of Morphine ARER, a Novel Abuse-Deterrent Formulation: Results from a Randomized, Double-Blind, Four-Way Crossover Study in Nondependent, Opioid-Experienced Subjects

OBJECTIVE: To investigate the pharmacokinetics (PK) of Morphine ARER, an extended-release (ER), abuse-deterrent formulation of morphine sulfate after oral and intranasal administration. METHODS: This randomized, double-blind, double-dummy, placebo-controlled, four-way crossover study assessed the PK...

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Detalhes bibliográficos
Publicado no:Pain Res Manag
Main Authors: Webster, Lynn R., Pantaleon, Carmela, Iverson, Matthew, Smith, Michael D., Kinzler, Eric R., Aigner, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937443/
https://ncbi.nlm.nih.gov/pubmed/29849845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7276021
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