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Inferring Fitness Effects from Time-Resolved Sequence Data with a Delay-Deterministic Model

A common challenge arising from the observation of an evolutionary system over time is to infer the magnitude of selection acting upon a specific genetic variant, or variants, within the population. The inference of selection may be confounded by the effects of genetic drift in a system, leading to...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Nené, Nuno R., Dunham, Alistair S., Illingworth, Christopher J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937181/
https://ncbi.nlm.nih.gov/pubmed/29500183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300790
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