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Fitness Inference from Short-Read Data: Within-Host Evolution of a Reassortant H5N1 Influenza Virus

We present a method to infer the role of selection acting during the within-host evolution of the influenza virus from short-read genome sequence data. Linkage disequilibrium between loci is accounted for by treating short-read sequences as noisy multilocus emissions from an underlying model of hapl...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Autor principal: Illingworth, Christopher J.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651230/
https://ncbi.nlm.nih.gov/pubmed/26243288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv171
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