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Amelioration of Pentylenetetrazole-Induced Seizures by Modulators of Sigma, N-Methyl-D-Aspartate, and Ryanodine Receptors in Mice

BACKGROUND: Sigma receptors, N-methyl-D-aspartate (NMDA) antagonist, and modulators of intracellular calcium may be useful for seizure control. Therefore, we aimed to evaluate the antiepileptic effects of opipramol, a sigma receptor agonist, against pentylenetetrazole (PTZ)-induced seizures in mice...

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Detalhes bibliográficos
Publicado no:Iran J Med Sci
Main Authors: Keshavarz, Mojtaba, Yekzaman, Behdad
Formato: Artigo
Idioma:Inglês
Publicado em: Iranian Journal of Medical Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936851/
https://ncbi.nlm.nih.gov/pubmed/29749988
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