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Sigma-1 and N-Methyl-d-Aspartate Receptors: A Partnership with Beneficial Outcomes
Sigma-1 receptors (σ-1R) are interorganelle signaling molecules, which have been implicated in synaptic plasticity, primarily by enhancing the function of N-methyl-d-aspartate receptors (NMDARs). On the other hand, excessive influx of calcium via activated NMDAR can cause excitotoxicity. Yet, despit...
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Publicado no: | Mol Neuropsychiatry |
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Principais autores: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
S. Karger AG
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4996022/ https://ncbi.nlm.nih.gov/pubmed/27602356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000376549 |
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