Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)

There is an unmet medical need for new subunit vaccines that induce cytotoxic T-lymphocyte (CTL) responses to prevent infection with a number of pathogens. However, stimulation of CTL responses via clinically acceptable subcutaneous (s.c.) and intramuscular (i.m.) injection is challenging. Recently,...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Schmidt, Signe Tandrup, Pedersen, Gabriel Kristian, Neustrup, Malene Aaby, Korsholm, Karen Smith, Rades, Thomas, Andersen, Peter, Foged, Camilla, Christensen, Dennis
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936752/
https://ncbi.nlm.nih.gov/pubmed/29760705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00898
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