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Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease

The endoplasmic reticulum (ER) stress response is regarded as an important process in the aetiology of Alzheimer's disease (AD). The accumulation of pathogenic misfolded proteins and the disruption of intracellular calcium (Ca(2+)) signalling are considered to be fundamental mechanisms that und...

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Bibliographische Detailangaben
Veröffentlicht in:Open Biol
Hauptverfasser: Hashimoto, Shoko, Saido, Takaomi C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936719/
https://ncbi.nlm.nih.gov/pubmed/29695619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.180024
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