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Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease

The endoplasmic reticulum (ER) stress response is regarded as an important process in the aetiology of Alzheimer's disease (AD). The accumulation of pathogenic misfolded proteins and the disruption of intracellular calcium (Ca(2+)) signalling are considered to be fundamental mechanisms that und...

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Bibliographic Details
Published in:Open Biol
Main Authors: Hashimoto, Shoko, Saido, Takaomi C.
Format: Artigo
Language:Inglês
Published: The Royal Society 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936719/
https://ncbi.nlm.nih.gov/pubmed/29695619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.180024
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