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2017 MILITARY SUPPLEMENT: CURRENT CHALLENGES IN THE DEVELOPMENT OF ACELLULAR HEMOGLOBIN OXYGEN CARRIERS BY PROTEIN ENGINEERING

This article reviews the key biochemical mechanisms that govern O(2) transport, NO scavenging, and oxidative degradation of acellular hemoglobin and how these ideas have been used to try to develop strategies to engineer safer and more effective hemoglobin-based oxygen carriers (HBOCs). Significant...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Benitez Cardenas, Andres S., Samuel, Premila P., Olson, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936680/
https://ncbi.nlm.nih.gov/pubmed/29112633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001053
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