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Modern Cross-linking Strategies for Synthesizing Acellular Hemoglobin-Based Oxygen Carriers

Unmodified cell-free hemoglobin (Hb) is structurally unstable when transfused into the blood stream (1-4). This review examines some of the latest chemical strategies used over the last five years to intra- and inter-molecularly cross-link Hb, thereby stabilizing its quaternary structure. Therefore,...

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Detalhes bibliográficos
Main Authors: Harris, David Raphael, Palmer, Andre Francis
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637476/
https://ncbi.nlm.nih.gov/pubmed/19194934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.85
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