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Modern Cross-linking Strategies for Synthesizing Acellular Hemoglobin-Based Oxygen Carriers
Unmodified cell-free hemoglobin (Hb) is structurally unstable when transfused into the blood stream (1-4). This review examines some of the latest chemical strategies used over the last five years to intra- and inter-molecularly cross-link Hb, thereby stabilizing its quaternary structure. Therefore,...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637476/ https://ncbi.nlm.nih.gov/pubmed/19194934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.85 |
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