Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1

Aberrant expression of ARE-binding proteins (ARE-BPs) plays an important role in several diseases, including cancer. Both tristetraprolin (TTP) and human antigen R (HuR) are important ARE-BPs and always play opposite roles in regulating target mRNAs. Our previous work has demonstrated that TTP expre...

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Udgivet i:Sci Rep
Main Authors: Wang, Hao, Chen, Yigang, Guo, Jian, Shan, Ting, Deng, Kaiyuan, Chen, Jialin, Cai, Liping, Zhou, Hong, Zhao, Qin, Jin, Shimao, Xia, Jiazeng
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935726/
https://ncbi.nlm.nih.gov/pubmed/29728635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25443-3
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