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Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis

The oligometastasis hypothesis suggests a spectrum of metastatic virulence where some metastases are limited in extent and curable with focal therapies. A subset of patients with metastatic colorectal cancer achieves prolonged survival after resection of liver metastases consistent with oligometasta...

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Vydáno v:Nat Commun
Hlavní autoři: Pitroda, Sean P., Khodarev, Nikolai N., Huang, Lei, Uppal, Abhineet, Wightman, Sean C., Ganai, Sabha, Joseph, Nora, Pitt, Jason, Brown, Miguel, Forde, Martin, Mangold, Kathy, Xue, Lai, Weber, Christopher, Segal, Jeremy P., Kadri, Sabah, Stack, Melinda E., Khan, Sajid, Paty, Philip, Kaul, Karen, Andrade, Jorge, White, Kevin P., Talamonti, Mark, Posner, Mitchell C., Hellman, Samuel, Weichselbaum, Ralph R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935683/
https://ncbi.nlm.nih.gov/pubmed/29728604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04278-6
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