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Investigation of the essential role of platelet-tumor cell interactions in metastasis progression using an agent-based model

BACKGROUND: Metastatic tumors are a major source of morbidity and mortality for most cancers. Interaction of circulating tumor cells with endothelium, platelets and neutrophils play an important role in the early stages of metastasis formation. These complex dynamics have proven difficult to study i...

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Detalhes bibliográficos
Main Authors: Uppal, Abhineet, Wightman, Sean C, Ganai, Sabha, Weichselbaum, Ralph R, An, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022382/
https://ncbi.nlm.nih.gov/pubmed/24725600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-11-17
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