Investigation of the essential role of platelet-tumor cell interactions in metastasis progression using an agent-based model

BACKGROUND: Metastatic tumors are a major source of morbidity and mortality for most cancers. Interaction of circulating tumor cells with endothelium, platelets and neutrophils play an important role in the early stages of metastasis formation. These complex dynamics have proven difficult to study i...

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Bibliographic Details
Main Authors: Uppal, Abhineet, Wightman, Sean C, Ganai, Sabha, Weichselbaum, Ralph R, An, Gary
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022382/
https://ncbi.nlm.nih.gov/pubmed/24725600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-11-17
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