Effect of Discontinuation or Initiation of Methotrexate or Glucocorticoids on Tofacitinib Efficacy in Patients with Rheumatoid Arthritis: A Post Hoc Analysis

INTRODUCTION: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). We evaluated the effect of concomitant methotrexate (MTX) or glucocorticoid (GC) use on tofacitinib clinical efficacy. METHODS: Data were pooled from two open-label, long-term extension studie...

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Publicado en:Rheumatol Ther
Autores principales: Fleischmann, Roy, Wollenhaupt, Jürgen, Cohen, Stanley, Wang, Lisy, Fan, Haiyun, Bandi, Vara, Andrews, John, Takiya, Liza, Bananis, Eustratios, Weinblatt, Michael E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Healthcare 2018
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935624/
https://ncbi.nlm.nih.gov/pubmed/29417430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40744-018-0093-7
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