Effect of Discontinuation or Initiation of Methotrexate or Glucocorticoids on Tofacitinib Efficacy in Patients with Rheumatoid Arthritis: A Post Hoc Analysis

INTRODUCTION: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). We evaluated the effect of concomitant methotrexate (MTX) or glucocorticoid (GC) use on tofacitinib clinical efficacy. METHODS: Data were pooled from two open-label, long-term extension studie...

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Vydáno v:Rheumatol Ther
Hlavní autoři: Fleischmann, Roy, Wollenhaupt, Jürgen, Cohen, Stanley, Wang, Lisy, Fan, Haiyun, Bandi, Vara, Andrews, John, Takiya, Liza, Bananis, Eustratios, Weinblatt, Michael E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Healthcare 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935624/
https://ncbi.nlm.nih.gov/pubmed/29417430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40744-018-0093-7
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