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Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity
Newly-formed synaptic vesicles (SVs) are rapidly acidified by vacuolar adenosine triphosphatases (vATPases), generating a proton electrochemical gradient that drives neurotransmitter loading. Clathrin-mediated endocytosis is needed for the formation of new SVs, yet it is unclear when endocytosed ves...
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| Publicado en: | eLife |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5935483/ https://ncbi.nlm.nih.gov/pubmed/29652249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32569 |
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