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Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place
Oncogene activation disturbs cellular processes and accommodates a complex landscape of changes in the genome that contribute to genomic instability, which accelerates mutation rates and promotes tumourigenesis. Part of this cellular turmoil, involves deregulation of physiological DNA replication, w...
Shranjeno v:
| izdano v: | Cancer Discov |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5935233/ https://ncbi.nlm.nih.gov/pubmed/29653955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-1461 |
| Oznake: |
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