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Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place

Oncogene activation disturbs cellular processes and accommodates a complex landscape of changes in the genome that contribute to genomic instability, which accelerates mutation rates and promotes tumourigenesis. Part of this cellular turmoil, involves deregulation of physiological DNA replication, w...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Kotsantis, Panagiotis, Petermann, Eva, Boulton, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935233/
https://ncbi.nlm.nih.gov/pubmed/29653955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-1461
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