The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells

The molecular mechanisms by which TGF-β and interleukin 4 (IL-4) signaling control the differentiation of IL-9-producing CD4(+) T (T(H)9) cells remain incompletely understood. We show here that the DNA-binding inhibitor Id3 regulated Th9 cell differentiation, as deletion of Id3 increased IL-9 produc...

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Publicat a:Nat Immunol
Autors principals: Nakatsukasa, Hiroko, Zhang, Dunfang, Maruyama, Takashi, Chen, Hua, Cui, Kairong, Ishikawa, Masaki, Deng, Lisa, Zanvit, Peter, Tu, Eric, Jin, Wenwen, Abbatiello, Brittany, Goldburg, Nathan, Chen, Qianming, Sun, Lingyun, Zhao, Keji, Chen, WanJun
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935106/
https://ncbi.nlm.nih.gov/pubmed/26322481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3252
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