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MARCH6 and TRC8 facilitate the quality control of cytosolic and tail‐anchored proteins
Misfolded or damaged proteins are typically targeted for destruction by proteasome‐mediated degradation, but the mammalian ubiquitin machinery involved is incompletely understood. Here, using forward genetic screens in human cells, we find that the proteasome‐mediated degradation of the soluble misf...
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| 出版年: | EMBO Rep |
|---|---|
| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5934766/ https://ncbi.nlm.nih.gov/pubmed/29519897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201745603 |
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