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MARCH6 and TRC8 facilitate the quality control of cytosolic and tail‐anchored proteins
Misfolded or damaged proteins are typically targeted for destruction by proteasome‐mediated degradation, but the mammalian ubiquitin machinery involved is incompletely understood. Here, using forward genetic screens in human cells, we find that the proteasome‐mediated degradation of the soluble misf...
Uloženo v:
| Vydáno v: | EMBO Rep |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5934766/ https://ncbi.nlm.nih.gov/pubmed/29519897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201745603 |
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