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Protein plasticity driven by disorder and collapse governs the heterogeneous binding of CytR to DNA

The amplitude of thermodynamic fluctuations in biological macromolecules determines their conformational behavior, dimensions, nature of phase transitions and effectively their specificity and affinity, thus contributing to fine-tuned molecular recognition. Unique among large-scale conformational ch...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Munshi, Sneha, Gopi, Soundhararajan, Subramanian, Sandhyaa, Campos, Luis A, Naganathan, Athi N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934615/
https://ncbi.nlm.nih.gov/pubmed/29538715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky176
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