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Identification of Loop D Domain Amino Acids in the Human Aquaporin-1 Channel Involved in Activation of the Ionic Conductance and Inhibition by AqB011

Aquaporins are integral proteins that facilitate the transmembrane transport of water and small solutes. In addition to enabling water flux, mammalian Aquaporin-1 (AQP1) channels activated by cyclic GMP can carry non-selective monovalent cation currents, selectively blocked by arylsulfonamide compou...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Kourghi, Mohamad, De Ieso, Michael L., Nourmohammadi, Saeed, Pei, Jinxin V., Yool, Andrea J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934433/
https://ncbi.nlm.nih.gov/pubmed/29755973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00142
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