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Glycan Shielding and Modulation of Hepatitis C Virus Neutralizing Antibodies

Hepatitis C virus (HCV) envelope glycoprotein heterodimer, E1E2, plays an essential role in virus entry and assembly. Furthermore, due to their exposure at the surface of the virion, these proteins are the major targets of anti-HCV neutralizing antibodies. Their ectodomain are heavily glycosylated w...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Lavie, Muriel, Hanoulle, Xavier, Dubuisson, Jean
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934428/
https://ncbi.nlm.nih.gov/pubmed/29755477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00910
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